Interleukin 16, aa502-631, Recombinant, Human, His-tag (IL-16, LCF, prIL-16, FLJ16806,
FLJ42735, FLJ44234, HST19289)
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| IL16, 502-631aa, Human, His-tagged, Recombinant, E. coli | | | Catalog # | I8438-01C | | Full name | Interleukin 16 | | Synonyms | LCF, prIL-16, FLJ16806, FLJ42735, FLJ44234, HST19289 | | Interleukin-16 (IL16) is an immunomodulatory cytokine, which induces lymphocyte migration, expression of proinflammatory IL-1 , IL6 and tumor necrosis factor-alpha (TNF ), and modulates apoptosis. This protein is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. Also, several central nervous system diseases and may play a role in promoting inflammatory responses. | | Recombinant human IL16, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. | | Molecular Weight | 15kD (150 aa) | | Sequence | MGSSHHHHHH SSGLVPRGSH MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 15kD | | Source | Recombinant, E. coli | | Purity | 95% by SDS PAGE | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris, pH 8.0, 1mM DTT, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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