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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 16, aa502-631, Recombinant, Human, His-Tag (IL-16, LCF, prIL-16, FLJ16806, FLJ42735, FLJ44234, HST19289)

Interleukin 16, aa502-631, Recombinant, Human, His-Tag (IL-16, LCF, prIL-16, FLJ16806,
FLJ42735, FLJ44234, HST19289)

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Specifications

IL16, 502-631aa, Human, His-tagged, Recombinant, E. coli
Catalog #I8438-01C
Full name Interleukin 16
Synonyms LCF, prIL-16, FLJ16806, FLJ42735, FLJ44234, HST19289
Interleukin-16 (IL16) is an immunomodulatory cytokine, which induces lymphocyte migration, expression of proinflammatory IL-1 , IL6 and tumor necrosis factor-alpha (TNF ), and modulates apoptosis. This protein is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. Also, several central nervous system diseases and may play a role in promoting inflammatory responses.
Recombinant human IL16, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Molecular Weight 15kD (150 aa)
Sequence MGSSHHHHHH SSGLVPRGSH MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight15kD
SourceRecombinant, E. coli
Purity95% by SDS PAGE
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris, pH 8.0, 1mM DTT, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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