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IL17A, Recombinant, Human (Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8, CTLA8, IL17)
IL17A, Recombinant, Human (Interleukin-17A, IL-17, IL-17A, Cytotoxic
T-lymphocyte-associated Antigen 8, CTLA-8, CTLA8, IL17)
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| Interleukin 17A (IL-17A) is the original member of the IL-17 family of structurally related cytokines (IL-17 A to IL-17F) that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17A is a pro-inflammatory cytokine produced primarily by T cells and is commonly associated with the allergic response facilitating the release of other cytokines, chemokines and prostaglandins from a variety of cell types. IL-17A exists in vitro as a homodimer of two 132aa chains. | | | Catalog # | I8439-02E | | Source | Recombinant corresponding to aa24-155 from human IL-17A monomer coding sequence, fused to 6x His-tag at N-terminal, expressed in E. coli. | | Applications | Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistohemistry, Immunoassays, Development of Rapid tests and other immunoassay. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Source | E. coli | | Purity | ~95% (SDS-PAGE) | | Concentration | As reported | | Form | Supplied as liquid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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