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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 17 (IL-17, CTLA8, IL-17A, Interleukin-17A Precursor, Cytotoxic T-lymphocyte-associated Antigen 8) (Biotin)

Anti -Interleukin 17 (IL-17, CTLA8, IL-17A, Interleukin-17A Precursor, Cytotoxic
T-lymphocyte-associated Antigen 8) (Biotin)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Purified E
Interleukin 17 is a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belongs to the IL-17 family (classified as IL-17A to IL-17F), and signals through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
Catalog #I8439-04L1
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10B2379
HostRat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide. Labeled with Biotin.
PurityPurified
ImmunogenMouse Interleukin 17.
SpecificityRecognizes mouse Interleukin 17.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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