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You are here:Home » Antibodies » Abs to Interleukin » Anti -Interleukin 17 (IL-17, CTLA8, IL-17A, Interleukin-17A Precursor, Cytotoxic T-lymphocyte-associated Antigen 8)

Anti -Interleukin 17 (IL-17, CTLA8, IL-17A, Interleukin-17A Precursor, Cytotoxic
T-lymphocyte-associated Antigen 8)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Mouse interleukin-17 (IL-17/IL-17A), a disulfide-linked homodimer and member of the IL-17
family, secreted primarily by activated CD4+ T cells, which signals through the IL-17 receptor (IL-17R). IL-17 induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. Increased levels of IL-17 are detectable during transplant rejection, and also during rheumatoid arthritis, possibly contributing to bone destruction.
Catalog #I8439-04P
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.5-2ug/ml
Western Blot: 0.1-0.2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS, pH. 7.2. No preservative added. Reconstitute with 100ul sterile 40-50% glycerol, ddH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant mouse IL-17.
SpecificityRecognizes mouse Interleukin 17.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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