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You are here:Home » Antibodies » Abs to Interleukin » Anti -IL17E (Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, UNQ3120/PRO10272)

Anti -IL17E (Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, UNQ3120/PRO10272)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8. Exposure of mice to IL17 resulted in a Th-2 like response characterized by increased serum IgE, IgG1 and IgA levels, blood eosinophilia, increased lymphocytes and neutrophils, and pathological changes in the tissues that included eosinophilic infiltrates, increased mucus production, B-lymphocyte hyperplasia and epithelial cell hyperplasia/hypertrophy.
Catalog #I8439-21A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No68C1039.2
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% sodium azide
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa115-132 from human IL-17E (KLH).
SpecificityRecognizes human IL-17E. Species sequence homology: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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