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Anti -IL17ra (Interleukin 17 receptor A, AW538159, Cdw217, IL17r, VDw217, Interleukin 17 receptor)
Anti -IL17ra (Interleukin 17 receptor A, AW538159, Cdw217, IL17r, VDw217, Interleukin 17
receptor)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| IL-17R, also known as IL-17RA, is a widely expressed 120kD glycosylated type I protein that plays a central role in inflammatory responses. IL-17R associates with IL-17RC to form a signaling receptor complex for IL-17 and IL-17F. IL-17R ligation promotes T cell activation and the production of IL-6, G-CSF, SCF, and multiple proinflammatory chemokines. Within the ECD, human IL-17R shares 72% aa sequence identity with mouse and rat IL-17R. | | | Catalog # | I8439-36 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:8000 | | Western Blot: 1-3ug/ml detects an ~10kDa band observed in Rat Kidney lysates (calculated MW of 96.1kDa according to Mouse NP_032385.1 and of 97.9kDa according to Rat NP_001101353.2). | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Rat | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-DQEKHGDDSKIN, from the internal region of rat IL17ra (NP_032385.1). | | Specificity | Recognizes rat IL17ra. Sequence homology: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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