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Anti -IL21 (Interleukin-21, IL-21, Za11)
Anti -IL21 (Interleukin-21, IL-21, Za11)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IC IF |
|
| A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations. | | | Catalog # | I8442-09A | | Applications | Suitable for use in Immunofluorescence, Western Blot and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 2ug/ml | | Western Blot: 0.5-1ug/ml | | Immunocytochemistry: 2ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human HL-60 and THP-1 cell lysates | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to human IL-21 (IN). | | Specificity | Recognizes human IL-21. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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