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Interleukin 21R, ED, Blocking Peptide (IL-21R ED)
Interleukin 21R, ED, Blocking Peptide (IL-21R ED)
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| A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21 (1). The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations. | | | Catalog # | I8442-25P | | Synthetic peptide (NITDQSGNYSQECGS) corresponding to amino acids 97 to 111 of human IL-21R precursor (1). | | Source | Synthetic peptide | | Purity | Purified 60-70% | | Concentration | ~0.2mg/ml | | Form | Supplied as a lyophilized powder. | | Specificity | Human Interleukin-21R. An approximately 60 kDa band can be detected. | | | Important Note | This product is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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