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Interleukin 21R, NT, Blockng Peptide (IL-21R NT)
Interleukin 21R, NT, Blockng Peptide (IL-21R NT)
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| A novel cytokine related to IL2 and IL15 was recently identified and designated IL-21 (1). The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations. | | | Catalog # | I8442-26P | | Synthetic peptide (CPDLVCYTDYLQT) corresponding to amino acids 20 to 32 of human IL-21R precursor (1). | | Concentration | ~0.2mg/ml | | Form | Supplied as a liquid at 200ug/ml in PBS, pH7.2 (10mM sodium phosphate monobasic, 10mM sodium phosphate dibasic, 130mM sodium chloride), 0.1% bovine serum albumin, 0.02% sodium azide. | | | | Intended for research use only, not for use in human, therapeutic or diagnostic applications. | | |
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