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Interleukin 31, Recombinant, Mouse (IL-31)
Interleukin 31, Recombinant, Mouse (IL-31)
Pricing
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| IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8kD protein containing 140 amino acid residues. | | | Catalog # | I8442-40 | | Source | E. coli | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile ddH2O, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. | | Country of Origin | USA | | Source | E. coli | | Purity | 98% by SDS-PAGE and HPLC analyses. | | Concentration | As reported | | Form | Supplied as a lyophilized powder from 20mM sodium phosphate, pH 7.5. | | Reconstitution | Reconstitute sterile ddH2O to a concentration of 0.1-1mg/ml, which can then be further diluted to other aqueous solutions. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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