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Anti -IL-32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor alpha-inducing Factor, IL32, NK4, TAIF)
Anti -IL-32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor
alpha-inducing Factor, IL32, NK4, TAIF)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| IL-32 is a 234aa protein belonging to the cytokine family and contains a tyrosine sulfation site, three potential N-myristoylation sites, multiple putative phosphorylation sites and an RGD cell-attachment sequence. It plays a role in activation-induced cell death in T cells, production of TNFalpha from macrophage cells and in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL-8 and activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. IL-32 appears to play a role in the pathogenesis of human rheumatoid arthritis and is a novel target in autoimmune diseases. It is expressed predominantly in lymphocytes and immune cells. | | | Catalog # | I8442-42 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 2.5-5ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to 16aa from human IL-32 (KLH). | | Specificity | Recognizes human IL-32. Species sequence homology: Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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