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You are here:Home » Antibodies » Abs to Interleukin » Anti -IL-32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor alpha-inducing Factor, IL32, NK4, TAIF)

Anti -IL-32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor
alpha-inducing Factor, IL32, NK4, TAIF)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
IL-32 is a 234aa protein belonging to the cytokine family and contains a tyrosine sulfation site, three potential N-myristoylation sites, multiple putative phosphorylation sites and an RGD cell-attachment sequence. It plays a role in activation-induced cell death in T cells, production of TNFalpha from macrophage cells and in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL-8 and activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. IL-32 appears to play a role in the pathogenesis of human rheumatoid arthritis and is a novel target in autoimmune diseases. It is expressed predominantly in lymphocytes and immune cells.
Catalog #I8442-42P
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa208-225 (SFQSYGAPRGDKEELTPQ) of human IL-32.
SpecificityRecognizes human IL-32.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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