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Anti -IL-32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor alpha-inducing Factor, IL32, NK4, TAIF)
Anti -IL-32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor
alpha-inducing Factor, IL32, NK4, TAIF)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E |
|
| IL-32 is the name given to the NK4 transcript first reported in IL-2 activated T lymphocytes and natural killer cells. IL-32 induces the degradation of inhibitory kappaB and phosphorylation of mitogen activated protein p38 and has a possible role in inflammatory:autoimmune diseases like chronic obstructive pulmonary disease, Crohn's disease and psoriasis. The protein activates typical cytokine signal pathways of nuclear factor-kappa B (NF-kappaB) and p38 mitogen-activated protein kinase. The protein contains a tyrosine sulfation site, three potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. It is selectively expressed in human lymphocytes. The gene encoding human IL-32 protein is localized on chromosome 16p13.3. | | | Catalog # | I8442-42Q | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:100-1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.025% sodium azide, 50% glycerol. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to aa210-227 ([BLAST]QSYGAPRGDKEELTPQKC[BLAST]) of human IL-32. | | Specificity | Recognizes human IL-32. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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