You are here:Home
»
Molecular Biology
»
MB-Peptides
»
Interleukin 32 alpha, Recombinant, Human (IL-32a, Interleukin-32 Precursor, Natural Killer Cells Protein 4, NK4, TAIF, TAIFa, Tumor Necrosis Factor alpha-inducing Factor)
Interleukin 32 alpha, Recombinant, Human (IL-32a, Interleukin-32 Precursor, Natural Killer
Cells Protein 4, NK4, TAIF, TAIFa, Tumor Necrosis Factor alpha-inducing Factor)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Human IL-32 alpha is one of approximately 6 splice variants of a gene cloned from the human lung carcinoma stable transfectant, A549-Rbeta. IL-32 alpha has been shown to induce IL-8, TNF-a, and MIP-2 production from human & mouse macrophage cell lines. It is upregulated in activated T- & NK-cells, and IFN-g-treated epithelial cells. | | | Catalog # | I8442-43 | | Endotoxin | 0.1EU/ug | | Biological Activity | Human IL-32 alpha activity is measured via the dose-dependent induction of TNF-alpha production from human PBMCs. The ED50 is in the range of 0.125-1ug/ml. | | AA Sequence | MCFPKVLSDD MKKLKARMHQ AIERFYDKMQ NAESGRGQVM SSLAELEDDF KEGYLETVAA YYEEQHPELT PLLEKERDGL RCRGNRSPVP DVEDPATEEP GESFCDKSYG APRGDKEELT PQKCSEPQSS K | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile water containing 0.1% HSA or BSA. Reconstituted product is stable for 6 months at -20ºC. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 14.9kD | | Source | Recombinant, human, produced in E. coli | | Purity | 97% as determined by reducing and non-reducing SDS-PAGE. | | Form | Supplied as a lyophilized powder from 50mM sodium phosphate, pH 7.5. Reconstiute with sterile water containing 0.1% HSA or BSA to a concentration of 0.1mg/ml. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
