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Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF)
Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4,
Tumor necrosis factor alpha-inducing factor, TAIF)
Pricing
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| Interleukin 32 isoform A belongs to cytokine family. This protein expression is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. It has the ability to induce proinflammatory cytokines such as TNF_ and IL8 in THP1 cells, and activates typical cytokine signaling pathways involving NF_B and p38. IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton. | | | Catalog # | I8442-43A | | Source | Recombinant human Interleukin 32, fused to His-tag at N-terminus, was expressed in E.coli. | | Molecular Weight | 19.1kD (168aa) | | AA Sequence | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCF PKVLSDDMKK LKARMHQAIE RFYDKMQNAE SGRGQVMSSL AELEDDFKEG YLETVAAYYE EQHPELTPLL EKERDGLRCR GNRSPVPDVE DPATEEPGES FCDKSYGAPR GDKEELTPQK CSEPQSSK | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 19.1kD | | Source | His-tagged, Recombinant, E. coli | | Purity | 95% (SDS-PAGE) | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl, pH8.0, 1mM DTT, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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