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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF)

Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4,
Tumor necrosis factor alpha-inducing factor, TAIF)

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Specifications

Interleukin 32 isoform A belongs to cytokine family. This protein expression is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. It has the ability to induce proinflammatory cytokines such as TNF_ and IL8 in THP1 cells, and activates typical cytokine signaling pathways involving NF_B and p38. IL-32 can also support osteoclast differentiation but not osteoclast activation by regulating the MAPK/ERK pathway and the actin cytoskeleton.
Catalog #I8442-43A
SourceRecombinant human Interleukin 32, fused to His-tag at N-terminus, was expressed in E.coli.
Molecular Weight 19.1kD (168aa)
AA SequenceMRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCF PKVLSDDMKK LKARMHQAIE RFYDKMQNAE SGRGQVMSSL AELEDDFKEG YLETVAAYYE EQHPELTPLL EKERDGLRCR GNRSPVPDVE DPATEEPGES FCDKSYGAPR GDKEELTPQK CSEPQSSK
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight19.1kD
SourceHis-tagged, Recombinant, E. coli
Purity95% (SDS-PAGE)
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris-HCl, pH8.0, 1mM DTT, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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