Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Neurofilament » Anti -Internexin, alpha

Anti -Internexin, alpha

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH IF
Alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. Many classes of mature neurons contain a-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons a-internexin is the only neurofilament subunit expressed. Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of a-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage.
Catalog #I8442-74
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:500 Formalin-fixed paraffin-embedded histological sections, cryostat sections.
Western Blot: 1:2500. Detects a band at 66kD.
Immunofluorescence: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH7.6, 0.05% sodium azide, 0.01% thimerosal, 15mg/ml BSA before the addition of glycerol to 40%.
PuritySerum
ImmunogenPurified recombinant rat a-internexin
SpecificityRecognizes a-internexin. Species Crossreactivity: Human and other mammalian samples.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links