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You are here:Home » Molecular Biology » Growth Factors-Interleukin » Interleukin 22, Recombinant, Mouse (IL-22, IL-10 Related T cell-derived Inducible Factor, IL-TIF)

Interleukin 22, Recombinant, Mouse (IL-22, IL-10 Related T cell-derived Inducible Factor,
IL-TIF)

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Specifications

Interleukin-22 (IL-22) is a regulatory cytokine and member of the IL-10 family, secreted by activated T cells, which signals through a class II cytokine receptor system consisting of IL-22R and IL-10R-beta/CRF2-4. IL-22 has been shown to act as an inhibitor of the production of IL-4 by Th2 cells, up-regulate the production of acute phase reactants in the pancreas and liver, and to be up-regulated in intestinal inflammation associated with Crohn’s disease.
Catalog #I8443-16A
SourceE. coli
ApplicationsSuitable for use in Functional Assays. Other applications not tested.
Biological ActivityDetermined by its ability to activate STAT following receptor ligand interaction.
Endotoxin 1EU/ug
Molecular Weight 33.4kD (146 amino acid residue homodimer)
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity98% (SDS PAGE and HPLC)
Concentration~0.1mg/ml
FormSupplied as a lyophilized powder. Reconstitute in 100ul distilled water.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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