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You are here:Home » Molecular Biology » MB-Growth Factors-Interleukin » Interleukin 23, Recombinant, Human (IL-23)

Interleukin 23, Recombinant, Human (IL-23)


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IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines (1). It exists as a heterodimer composed of the IL-12 p40 subunit and a novel p19 subunit (2). IL-23 is secreted by activated dendritic cells, macrophages, and monocytes.
Catalog #I8443-40D
Produced in HEK 293 cells. Mature human IL-23 (interleukin-23) p40 peptide (aa23-328) is fused at the C-terminus to a 18aa linker peptide, GSTSGSGKPGSGEGSTKG and to the mature p19 peptide (aa20-189) and fused at the N-terminus to a FLAG®-tag.
Biological Activity Induction of IL-17 secretion by mouse splenocytes.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity90% (SDS-PAGE)
Endotoxin0.1EU/ug protein (LAL).
FormSupplied as a sterile-filtered liquid in PBS.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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