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Interleukin 23, Recombinant, Human (IL-23) (Human 293 Cells)
Interleukin 23, Recombinant, Human (IL-23) (Human 293 Cells)
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| Catalog # | I8443-40G | | Human Cell Expression Cytokines | Expression of proteins in our Human 293-cell expression system is a cost-effective and scalable production method for high-authenticity, recombinant human proteins. | | IL-23 is expressed as a 55kD heterodimeric cytokine composed of two glycosylated and disulfide-linked subunits (p40 cystine linked to p19). Production in human 293 cells offers authentic glycosylation. Cytokines produced in SF9 or SF21 cells have post-translational modifications which are not human-like. | | Source | Recombinant Human IL-23 Expressed in Human 293 Cells. | | Activity | The specific activity was determined by the dose-dependent secretion of IL-17 from mouse | | splenocytes activated with 10ng/ml PMA. | | Specific Activity | 2 to 20 ng/mL ED50 | | Endotoxin | 1EU/ug (LAL) | | Storage and Stability | The cytokine can be stored at 4°C for short term only, or at -20°C to -80°C in aliquots for long | | term purpose. Avoid repeated freeze-thaw cycles. Reconstituted products are stable for 12 months at -20°C to -80°C from date of receipt. | | Molecular Weight | 55kD | | Source | Human 293 cells | | Purity | 95% as determined by SDS-PAGE and HPLC. | | Form | Supplied as a liquid in PBS, pH 7.4. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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