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You are here:Home » Antibodies » Abs to Interleukin » Anti -IL23A, NT (Interleukin-23 Subunit alpha, IL-23 Subunit alpha, IL-23-A, Interleukin-23 Subunit p19, IL-23p19, SGRF, UNQ2498/PRO5798)

Anti -IL23A, NT (Interleukin-23 Subunit alpha, IL-23 Subunit alpha, IL-23-A,
Interleukin-23 Subunit p19, IL-23p19, SGRF, UNQ2498/PRO5798)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-g, IL-12, and TNF-a from activated T cells, and can stimulate macrophages to produce TNF-a and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Catalog #I8443-40M
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Immunohistochemistry: 2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlMouse pancreas tissue lysate
Control Peptide I8443-40P
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to 16aa from human IL-23, at N-terminal.
SpecificityRecognizes human IL-23. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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