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You are here:Home » Antibodies » Antibodies-Interleukin » Anti -IL23A, NT (Interleukin-23 Subunit alpha, IL-23 Subunit alpha, IL-23-A, Interleukin-23 Subunit p19, IL-23p19, SGRF, UNQ2498/PRO5798)

Anti -IL23A, NT (Interleukin-23 Subunit alpha, IL-23 Subunit alpha, IL-23-A,
Interleukin-23 Subunit p19, IL-23p19, SGRF, UNQ2498/PRO5798)


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Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-g, IL-12, and TNF-a from activated T cells, and can stimulate macrophages to produce TNF-a and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Catalog #I8443-40M
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Immunohistochemistry: 2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlMouse pancreas tissue lysate
Control Peptide I8443-40P
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, 0.02% sodium azide.
ImmunogenSynthetic peptide corresponding to 16aa from human IL-23, at N-terminal.
SpecificityRecognizes human IL-23. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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