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You are here:Home » Molecular Biology » Growth Factors-Interleukin » Interleukin 17E, Recombinant, Rat, (IL-17E, IL25, IL-25, Precursor, interleukin 25, Interleukin-25)

Interleukin 17E, Recombinant, Rat, (IL-17E, IL25, IL-25, Precursor, interleukin 25,
Interleukin-25)

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Specifications

Interleukin-17E (IL-17E), also commonly called IL-25, is a pro-inflammatory cytokine member of a six-species family of proteins (IL-17A-17F). IL-17F stimulates secretion of IL-8 and induces activation of NF-kB by binding to the receptor IL- 17RB. Recombinant rat IL-17E is a non-glycosylated, disulfide-linked homodimer, containing two 145aa proteins and having a total molecular mass of 35.5kD.
Catalog #I8443-61
Biological ActivityThe activity is measured by the dose-dependent induction of human PBMCs and is typically <100ng/ml.
Amino Acid SequenceCSHLPRCCPS KQQEFPEEWL KWNPAPVSPP EPLRHTHHPE SCRASKDGPL NSRAISPWSY ELDRDLNRVP QDLYHARCLC PHCVSLQTGS HMDPMGNSVP LYHNQTVFYR RPCHGEQGAH GRYCLERRLY RVSLACVCVR PRMMA
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 20mM HCl, 0.1% BSA or HSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight35.5kD
SourceRecominant rat, expressed in E. coli
Purity~95% Analysis by RP-HPLC; Reducing and non-reducing SDS-PAGE. Endotoxin: 0.1ng/ml
FormSupplied as a lyophilized powder. Reconstitute with sterile 20mM HCl to 0.1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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