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Anti -IL-27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28, IL27A)
Anti -IL-27 (Interleukin-27 Subunit alpha, IL-27 Subunit alpha, IL-27-A, IL27-A, p28,
IL27A)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Recently, a new heterodimeric cytokine termed IL-27 that consists of EBI3 (Epstein-Barr virus-induced gene 3), an IL-12p40-related protein, and p28, a newly discovered IL-12p35-related polypeptide has been discovered0. IL-27 is involved in early Th1 initiation. Its action is mediated through the orphan cytokine receptor WSX-1/TCCR and gp130. IL-27 may also play a role in the induction of T-bet expression and regulation of Ig class switching in B cells. | | | Catalog # | I8443-75L | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1-2ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Jurkat, NIH 3T3 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide. | | Purity | Purified by Protein G affinity Chromatography. | | Immunogen | Synthetic peptide corresponding to aa31-46 (RPPGRPQLSLQELRRE) of human IL-27 (p28 subunit) of (Genbank accession number NP_663634.) | | Specificity | Recognizes human IL-27. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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