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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin-27, p28, Recombinant, Mouse (M-IL-27,p28)

Interleukin-27, p28, Recombinant, Mouse (M-IL-27,p28)

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Specifications

Recombinant Murine IL-27/p28 Subunit is a proinflammatory cytokine inducing immunomodulatory effects.
Catalog #I8443-76
Biological Activity Mouse p28 biological activity was measured via dose-dependent inhibition of TGF-beta and IL-6-induced IL-17A expression in mouse CD4 slpenocytes. 50ng/ml of mouse p28 is capable of inhibiting >25% of IL-17-A expression in this assay.
AA SequenceMFPTDPLSLQ ELRREFTVSL YLARKLLSEV QGYVHSFAES RLPGVNLDLL PLGYHLPNVS LTFQAWHHLS DSERLCFLAT TLRPFPAMLG GLGTQGTWTS SEREQLWAMR LDLRDLHRHL RFQVLAAGFK CSKEEEDKEE EEEEEEEEKK LPLGALGGPN QVSSQVSWPQ LLYTYQLLHS LELVLSRAVR DLLLLSLPRR PGSAWDS
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceRecombinant, murine, E. coli
Purity~95% as determined by: Reducing and non-reducing SDS-PAGE.
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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