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Involucrin, Recombinant, Human
Involucrin, Recombinant, Human
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| Involucrin is a soluble cytoplasmic protein precursor of the epidermal cornfied envelope that becomes cross-linked by transglutaminase during envelope assembly. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea which lacks a distinct cornfied layer. The protein is a useful marker of terminal differentiation. It is tightly linked to the onset of differentiation and first expressed in the immediate suprabasal layers of the epidermis. | | | Catalog # | I8447-26 | | Applications | • ELISA • Inhibition Assays • Western Blotting | | Stability | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles. | | Molecular Weight | 41kD | | Source | E. coli | | Purity | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 41kD | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in 50mM Tris-acetate, pH 7.5, 1mM EDTA and 20% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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