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You are here:Home » Biochemicals » Biochem-Antibiotics » Ionomycin

Ionomycin

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Specifications

Ionomycin was isolated from Streptomyces conglobatus as a potent antibiotic selective for Gram +ve bacteria. During the isolation it was recognised that ionomycin exhibits a very high affinity and selectivity for calcium ions suggesting the metabolite acts as a calcium ionophore. More recently, ionomycin has been used in cell biology as a universal calcium ionophore to explore the role of calcium regulation in the cell.
Catalog #I8447-50B
SolubilitySoluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards All products should be handled by qualified personnel only, trained in laboratory procedures.
CAS Number56092-81-0
Molecular FormulaC41H72O9
Molecular Weight~709kD
SourceStreptomyces conglobatus
Purity~98% (HPLC)
FormSupplied as a waxy solid


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