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You are here:Home » Antibodies » Antibodies-Prostaglandins » Anti -IP Receptor (PGI2 Receptor, Prostaglandin I2 Receptor)

Anti -IP Receptor (PGI2 Receptor, Prostaglandin I2 Receptor)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Prostaglandin I2 (PGI2) is a potent vasorelaxant and inhibitor of human platelet aggregation.1 Research of the PGI2 receptor (IP receptor) also demonstrates its participation in signal transduction of the pain response, cardioprotection, and inflammation.2,3,4,5,6 Cloning of the murine and human IP receptors reveals a significant amino-terminal truncation of the human IP receptor compared to the murine receptor.7,8 Accordingly, this antibody is useful only for immunochemical analysis of murine and rat samples. This polyclonal antibody detects a 67 kD band from murine neural tissues and platelets.
Catalog #I8448-90
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:200
Optimal dilution to be determined by researcher
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in TBS, pH 7.4, 0.1% BSA. 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to N-terminal aa3-16, MMASDGHPGPPSVT, of mouse prostaglandin I2 receptor (IP receptor).
SpecificityRecognizes mouse IP receptor. Does not cross-react with human IP receptor. Species Crossreactivity: rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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