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You are here:Home » Antibodies » Antibodies-Growth Factors, Cytokines » Anti -IP-10 (Interferon gamma Inducible 10kD Protein, Chemokine CXC Motif Ligand 10, CXCL10, CRG2)

Anti -IP-10 (Interferon gamma Inducible 10kD Protein, Chemokine CXC Motif Ligand 10,


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH FC IF
Interferon-gamma-inducible 10kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.
Catalog #I8449-06A
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunohistochemistry, Immunofluoresence and ELISA. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:50
Western Blot: 1:50
Immunohistochemistry (frozen): 1:50
Optimal dilutions to be determined by the researcher.
Positive Control Activated plasmacytoid dendritic cells
Negative Control Normal liver
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No6A585
FormSupplied as a liquid in PBS, 0.02% sodium azide, 0.1% BSA.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman IP-10.
SpecificityRecognizes human IP-10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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