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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -IP-10 (Interferon gamma Inducible 10kD Protein, Chemokine CXC Motif Ligand 10, CXCL10, CRG2)

Anti -IP-10 (Interferon gamma Inducible 10kD Protein, Chemokine CXC Motif Ligand 10,
CXCL10, CRG2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH FC IF
Interferon-gamma-inducible 10kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.
Catalog #I8449-06A
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunohistochemistry, Immunofluoresence and ELISA. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:50
Western Blot: 1:50
Immunohistochemistry (frozen): 1:50
Optimal dilutions to be determined by the researcher.
Positive Control Activated plasmacytoid dendritic cells
Negative Control Normal liver
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No6A585
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide, 0.1% BSA.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman IP-10.
SpecificityRecognizes human IP-10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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