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Anti -IP-10 (Interferon gamma Inducible 10kD Protein, Chemokine CXC Motif Ligand 10, CXCL10, CRG2)
Anti -IP-10 (Interferon gamma Inducible 10kD Protein, Chemokine CXC Motif Ligand 10,
CXCL10, CRG2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH FC IF |
|
| Interferon-gamma-inducible 10kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. | | | Catalog # | I8449-06A | | Applications | Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry, Immunofluoresence and ELISA. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:50 | | Western Blot: 1:50 | | Immunohistochemistry (frozen): 1:50 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Activated plasmacytoid dendritic cells | | Negative Control | Normal liver | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 6A585 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide, 0.1% BSA. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Human IP-10. | | Specificity | Recognizes human IP-10. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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