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Specifications

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant human IP-10 is an 8.5kD protein consisting of 77 amino acids including four conserved cysteine residues present in CXC chemokine.
Catalog #	I8449-10
Biological Activity	Determined by its ability to chemoattract human T lymphocytes using a concentration range of 10-50ng/ml
Storage and Stability	Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile ddH2O and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight	8.6kD
Source	Reombinant Human (E. coli)
Purity	98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug
Form	Supplied as a lyophilized powder. Reconstitute with sterile, ddH2O to a concentration of 0.1-1mg/ml. This solution can be diluted into water or other buffered solutions.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.