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You are here:Home » Molecular Biology » MB-Enzymes, Phosphatase » IPP-1, aa1-171, Recombinant, Human, His-tag (Inhibitor of Protein Phosphatase)

IPP-1, aa1-171, Recombinant, Human, His-tag (Inhibitor of Protein Phosphatase)

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Specifications

IPP-1, 1-171aa, Human, His-tagged, Recombinant, E. coli
Catalog #I8465-02B
Full name Protein phosphatase inhibitor-1
NCBI Accession NP_006732
Synonyms IPP-1, I-1, PPI-1
Protein phosphatase inhibitor-1 (IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B).
Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Molecular Weight 20kD (179 aa)
Sequence MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI
DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE
PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE
PSTKEPSTHI PPLDSKGANS VLEHHHHHH
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight20kD
SourceRecombinant, E. coli
Purity90% by SDS PAGE
Concentration~1mg/ml
FormSupplied as a liquid in 50mM Tris, pH 8.0, 0.1mM PMSF, 1mM EDTA, 1mM DTT, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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