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You are here:Home » Biochemicals » Biochem-Molecular Biology » IQ-1 (2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide)

IQ-1
(2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide)

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Specifications

Cell-permeable. Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents -catenin from switching coactivator usage from CBP to p300. The increase in -cateinin/CBP mediated transcription at the expense of - cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency.
Catalog #I8565
Storage and StabilityLyophilized powder may be stored at 4°C. Stable for 12 months at 4°C. Reconstitute with sterile DMSO. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Reconstituted product is stable for 6 months at 4°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number331001-62-8
Molecular FormulaC21H22N4O2
Molecular Weight362.42D
Purity~95% (HPLC)
FormSupplied as an orange solid. Reconstitute with DMSO.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide


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