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You are here:Home » Antibodies » Abs to Insulin » Anti -Insulysin (IDE, insulin-degrading enzyme, FLJ35968, Insulinase, Insulin-degrading Enzyme, Insulin Protease)

Anti -Insulysin (IDE, insulin-degrading enzyme, FLJ35968, Insulinase, Insulin-degrading
Enzyme, Insulin Protease)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Insulysin, a wide expressed protein, is responsible for the degradation of insulin in cells. Primarily located in the cytosol, insulysin has been isolated from many different tissues and cell lines, and can degrade intact insulin, insulin B-chain, glucagon, denatured hemoglobin, alpha-amyloid protein, TGF-alpha and amylin. Recent work implicates insulysin in clearing beta amyloid plaques from the brain, and has generated much interest in Alzheimer's disease research.
Catalog #I8601-02B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QQYNYDRDNIE, from the internal region of mouse IDE (NP_112419.2).
SpecificityRecognizes mouse IDE. Species crossreactivity: rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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