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You are here:Home » Antibodies » Abs to Protein Kinase Substrates » Anti -IRS-2, phosphorylated (Tyr978) (Insulin Receptor Substrate 2, IRS2)

Anti -IRS-2, phosphorylated (Tyr978) (Insulin Receptor Substrate 2, IRS2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E Gel
Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Catalog #I8700-18P
ApplicationsSuitable for use in ELISA and Dot Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Dot Blot: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to amino acid residues surrounding Tyr978 of human IRS2 (KLH).
SpecificityRecognizes human IRS2 when phosphorylated at Tyr978.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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