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You are here:Home » Antibodies » Abs to Drugs » Anti -Ivermectin

Anti -Ivermectin

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Purified E
Anthelmintics or anti-helminthics are a class of drugs that are effective against a range of intestinal parasitic worms (helminths). Parasitic helminths must maintain an appropriate feeding site. Nematodes and trematodes must actively ingest and move food through their digestive tracts to maintain an appropriate energy state; these together with reproductive processes require a well defined and developed neuromuscular coordination. Anthelmintic treatment is a multi-targeting system designed to interfere with the integrity of parasite cells. The pharmacologic basis of the treatment for helminths involves the targeting of neuromuscular coordination, or protective mechanisms against host immunity, which lead to starvation, paralysis, and expulsion of the parasite. The benzimidazole class of drugs were introduced in 1961 and interfere with the parasite's ATP pathway on a cellular level. They bind to a specific building block called b-tubulin and prevent its incorporation into certain cellular structures called microtubules, which are essential for energy metabolism.
Catalog #I9900-04
ApplicationsSuitable for use in ELISA and in the development of immunoassays or immunoaffinity purification columns. Other applications not tested.
Recommended DilutionELISA: 15ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostSheep
Concentration~1mg/ml
FormSupplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.
PurityPurified
ImmunogenIsoxsuprine (p-OH) (BTG)
SpecificityRecognizes vermectin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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