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You are here:Home » Antibodies » Abs to Notch Proteins » Anti -Jag1 (Protein Jagged-1, Jagged1, CD339)

Anti -Jag1 (Protein Jagged-1, Jagged1, CD339)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Jagged belongs to the Delta-Serrate-Lag-2 (DSL) family of ligands that activate LIN12/Notch proteins. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged 1is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis. Mutation in Jagged1 is associated with an autosomal dominant disorder known as Alagille syndrome and Familial Tetralogy of Fallot a form of complex congenital heart disease.
Catalog #J0400-01R
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa114 from rat Jagged 1.
SpecificityRecognizes mouse Jagged 1. Species Crossreactivity: human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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