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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -JPO2 (CDCA7L, RAM2, Cell Division Cycle-associated 7-like Protein, Protein JPO2, Transcription Factor RAM2, HR1, R1)

Anti -JPO2 (CDCA7L, RAM2, Cell Division Cycle-associated 7-like Protein, Protein JPO2,
Transcription Factor RAM2, HR1, R1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Cell division cycle-associated 7-like protein (or RAM2) is a transcription factor which plays a role in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Catalog #J5550-50A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 2-5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHCT-116 (human) and NIH 3T3 (mouse) cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa170-220 of human JPO2.
SpecificityRecognizes human JPO2. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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