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You are here:Home » Antibodies » Abs to Retinoblastoma Proteins » Anti -Jumonji/ARID Domain Containing Protein 1A (JARID1A, KDM5A, Retinoblastoma Binding Protein 2, RBBP2, RBP2, Retinoblastoma Binding Protein 2 Homolog, RBP2-H1)

Anti -Jumonji/ARID Domain Containing Protein 1A (JARID1A, KDM5A, Retinoblastoma Binding
Protein 2, RBBP2, RBP2, Retinoblastoma Binding Protein 2 Homolog, RBP2-H1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Catalog #J7876-08
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Proximity Ligation Assay and Immunoprecipitation. Other applications not tested.
Recommended DilutionsWestern Blot: 1:2000-1:10,000
Immunohistochemistry (Frozen and Paraffin): 1:10-1:500
Proximity Ligation Assay: 1:200-1:4000
Immunoprecipitation: 4-10ug/mg lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide
PurityPurified by immunoaffinity chromatography
ImmunogenThe epitope recognized maps to a region between residue 1675 and 1690 of human Jumonji/ARID Domain-Containing Protein 1A using the numbering given in entry NP_005047.1 (GeneID 5927).
SpecificityRecognizes human Jarid1A/RBP2 protein. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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