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You are here:Home » Antibodies » Abs to Retinoblastoma Proteins » Anti -Jumonji/ARID Domain Containing Protein 1A (JARID1A, KDM5A, Retinoblastoma Binding Protein 2, RBBP2, RBP2, Retinoblastoma Binding Protein 2 Homolog, RBP2-H1)

Anti -Jumonji/ARID Domain Containing Protein 1A (JARID1A, KDM5A, Retinoblastoma Binding
Protein 2, RBBP2, RBP2, Retinoblastoma Binding Protein 2 Homolog, RBP2-H1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Catalog #J7876-08
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.
PurityPurified by peptide immunoaffinity chromatography.
ImmunogenThe epitope recognized maps to a region between residue 1675 and the C-terminus (residue 1722) of human Jumonji/ARID Domain-Containing Protein 1A/Retinoblastoma Binding Protein 2 Homolog 1 using the numbering given in entry NP_005047.1 (GeneID 5927).
SpecificityThis antibody is specific to the Jarid1A/RBP2 protein. Species Crossreactivity: Human and mouse. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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