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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -Jumonji Domain Containing 2C (JMJD2C, JMJD2, Gene Amplified in Squamous Cell Carcinoma 1, GASC1, JmjC Domain Containing Histone Demethylation Protein 3C, JHDM3C, KDM4C)

Anti -Jumonji Domain Containing 2C (JMJD2C, JMJD2, Gene Amplified in Squamous Cell
Carcinoma 1, GASC1, JmjC Domain Containing Histone Demethylation Protein 3C, JHDM3C,
KDM4C)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Jumonji Domain Containing 2C is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
Catalog #J7876-47
ApplicationsSuitable for use in Western Blot, Chromatin Immunoprecipitation and Immunoprecipitation. Other applications not tested.
Recommended DilutionsWestern Blot: 1:2000-1:10,000
Immunoprecipitation: 1:2000-1:10,000
Chromatin Immunoprecipitation: 1:10-1:500
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa whole cell extract
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in Tris-citrate/phosphate buffer, pH 7.5, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
SpecificityRecognizes human Jumonji Domain Containing 2C protein. The epitope recognized maps to a region between aa475-525 of human Jumonji Domain Containing 2C protein (NP_055876.2).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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