Anti -Junctional Adhesion Molecule 1 (JAM 1, JAM-1, JAM1, CD321, ESTM33, F11 Receptor, F11R, Junctional Adhesion Molecule A, JAM-A, JAMA, JCAM, Jcam1, Ly106, Platelet Adhesion Molecule 1, PAM-1, PAM1, Platelet F11 Receptor)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
FC IF |
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| Junctional adhesion molecule-1 (JAM-1) also known as the mouse platelet F11-Receptor (F11R) is a cell adhesion molecule (CAM). JAM-1 is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-1 belongs together with JAM-2 and JAM-3 to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-1 plays a role in platelet aggregation, secretion, adhesion and spreading. | | | Catalog # | J8009-04M | | Applications | Suitable for use in Flow Cytometry and Immunofluorescence. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:10. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | BV12 | | Host | Rat | | Source | Mouse | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Mouse Junctional Adhesion Molecule 1. | | Specificity | Recognizes mouse Junctional Adhesion Molecule 1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 9130004G24, AA638916, CD321 Antigen, JAM |
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Download Specifications for Anti -Junctional Adhesion Molecule 1 (JAM 1, JAM-1, JAM1, CD321, ESTM33, F11 Receptor, F11R, Junctional Adhesion Molecule A, JAM-A, JAMA, JCAM, Jcam1, Ly106, Platelet Adhesion Molecule 1, PAM-1, PAM1, Platelet F11 Receptor) |
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