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You are here:Home » Antibodies » Abs to Kallikrein » Anti -Kallikrein B1 (KLKB1, Plasma Kallikrein)

Anti -Kallikrein B1 (KLKB1, Plasma Kallikrein)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B
Kallikrein B1 (KLKB1) is a serine protease synthesized in the liver and circulated in the plasma by binding to high molecular weight (HMW) kininogen or as a free zymogen. It plays an important role in blood pressure regulation, fibrinolysis, and neutrophil activation. Mouse KLKB1 precursor contains a signal peptide (residues 1 to 19) and a pro form sequence (residues 20 to 638). Upon activation, the pro form is converted to a heavy chain and a light chain, which is linked by disulfide bonds and the latter contains the catalytic domain. The amino acid sequence of mouse KLKB1 is 90%, 77% and 76% identical to that of rat, canine and human.
Catalog #K0005-28B
ApplicationsSuitable for use in Western Blot and ELISA. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
ELISA: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No7H97
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived recombinant mouse KLKB1 (aa20-638) Accession # NP_032481
SpecificityRecognizes mouse Kallikrein B1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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