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You are here:Home » Biochemicals » Biochem-Antibiotics » Kanamycin Sulfate

Kanamycin Sulfate

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Specifications

Kanamycin sulfate is an antibiotic that belongs to the group of drugs called aminoglycosides. It binds to ribosomal components and inhibits protein synthesis. Kanamycin sulfate appears to prevent bacteria from making their cell walls, thus the cells die. It is used to treat many sensitive gram-negative, some gram-positive bacteria and and mycoplasmas in cell culture. Kanamycin is inactivated by an aminoglycoside phospho transferase (MW 25,000) in the periplasmic space.
Catalog #K0010
ApplicationSuitable for use as a selectable marker for cosmid vectors used in transfection of mammalian cells.
Activity on Dry Basis 750ug/mg
AppearanceWhite to light tan crystalline powder
IdentityTo pass USP Test
Kanamycin B Content 4%
Specific Rotation+112° to +123°
Loss on Drying 1.5%
pH6.5-8.5
Endotoxin 2Eu/mg
Working ConcentrationCell/Tissue Culture: ~30ug/ml
Stringent Plasmids: 10ug/ml
Relaxed Plasmids: 50ug/ml
CAS Number25389-94-0
Molecular FormulaC18H36N4O11H2SO4
Molecular Weight582.58
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesStreptomyces kanamyceticus; Kanamycin A; Kanamycin monosulfate


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