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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -KAP (Kidney Androgen-regulated Protein, ARP, FKSG22)

Anti -KAP (Kidney Androgen-regulated Protein, ARP, FKSG22)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
KAP is a second dual specificity phosphatase that interacts with cyclin-dependent kinases. KAP contains the HCXXXXGR motif characteristic of protein tyrosine phosphatases and exhibits phosphatase activity toward substrates containing either phosphotyrosine or phosphoserine residues. The ability of KAP to bind multiple cyclin-dependent kinases suggests that it may be a critical control element in cell cycle regulation, presumably by regulating phosphorylation state of a Cdk or Cdk- associated protein.
Catalog #K0075-02
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 2-4ug/ml for 2h at RT
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa cells, lung tumor
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa195-212 from human KAP.
SpecificityRecognizes human KAP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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