Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -KBRAS2 (NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2, NKIRAS2)

Anti -KBRAS2 (NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting
Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2, NKIRAS2)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
KappaB ras-1 and kB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkappaB (IkB), an inhibitor of the transcription factor NF-kB. IkB exists in two homologous forms, IkB-a and IkB-b, although IkB-b contains a unique 47aa region within its ankyrin domain. While inactive IkB-a-NF-kB complexes can shuttle in and out of the nucleus, IkB-b-NF-kB complexes are retained exclusively in the cytoplasm. It is suggested that kB-ras proteins preferentially bind to the IkB-b form through this unique insert within the ankyrin region, thus modulating the cellular location of IkB-b and regulating the rate of degradation of IkB-b. This antibody is specific for kB-ras2 and has no cross-reactivity to kBras1.
Catalog #K0079-52A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlRAW264.7 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to 14aa from near the C-terminus of human KappaB ras2.
SpecificityRecognizes human KappaB ras2. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links