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You are here:Home » Antibodies » Abs to IgG Kappa » Anti -Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809)

Anti -Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa
Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km,
MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH
Useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas. The most common feature of these malignancies is the restricted expression of a single light chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Immunoglobulin bearing Kappa light chains are present on about 60% of normal B lymphocytes.
Catalog #K0090-02C
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionIndirect ELISA Titer: 1:50,000
Immunohistochemistry: Frozen or paraffin-embedded sections.
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells of Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No5E697
HostMouse
SourceHuman
Concentration~2mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide before the addition of glycerol to 40%.
PurityPurified by Protein A affinity chromatography.
ImmunogenMixture of light chains of human immunoglobulins.
SpecificityRecognizes the independent constantly expressed epitope of kappa chain. Reacts with free and heavy chain-associated kappa chains.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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