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You are here:Home » Antibodies » Abs to IgG Kappa » Anti -Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809)

Anti -Kappa Light Chain (HCAK1, Ig kappa Chain C Region, IGKC, Immunoglobulin kappa
Constant Region, Immunoglobulin kappa Light Chain, Kappa 1 Immunoglobulin Light Chain, Km,
MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant E IH
Useful in the identification of leukemias, plasmacytomas and certain non-Hodgkin’s lymphomas. The most common feature of these malignancies is the restricted expression of a single light chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Immunoglobulin bearing Kappa light chains are present on about 60% of normal B lymphocytes.
Catalog #K0090-20
ApplicationsSuitable for use in ELISA and Immunohistochemistry (frozen and paraffin sections, proteolytic treatment with trypsin required).
Recommended DilutionImmunohistochemistry: 1:5-1:10; Incubation Time 1 hr at room temperature.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No5F258
HostMouse
ConcentrationNot determined
FormSupplied as a liquid.
PurityCulture supernatant
ImmunogenIsolated from Bence Jones kappa proteins.
SpecificityAntigen Recognized Human in Species (tested so far). Recommended for Bone marrow. Reacts with kappa light chains of secreted immunoglobulins and with Ig on the surface of B lymphocytes.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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