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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -Karyopherin alpha 1 (KPNA1, Importin alpha 5, IPOA5, Importin alpha 1 Subunit, Importin alpha S1, mSRP1, Nucleoprotein Interactor 1, NPI1, Recombination Activating Gene Cohort 2, RAG Cohort Protein 2, RCH2, SRP1 beta)

Anti -Karyopherin alpha 1 (KPNA1, Importin alpha 5, IPOA5, Importin alpha 1 Subunit,
Importin alpha S1, mSRP1, Nucleoprotein Interactor 1, NPI1, Recombination Activating Gene
Cohort 2, RAG Cohort Protein 2, RCH2, SRP1 beta)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The KPNA1 product interacts with RAG1 and may play a role in V(D)J recombination.
Catalog #K0102-02D
Cellular Localization Cytoplasmic
Positive Control HEK293, HeLa and HEPG2
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer,
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide TTPGKENFRLKSY, representing the N-Terminus of the human protein (residues 2-14) according to NP_002255.
SpecificitySpecies Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse (100% identity with immunogen) and Rat due to sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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