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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -KPNA4 (Importin alpha-4 Subunit, Karyopherin alpha-4 Subunit, Importin alpha Q1, Importin alpha-4, QIP1)

Anti -KPNA4 (Importin alpha-4 Subunit, Karyopherin alpha-4 Subunit, Importin alpha Q1,
Importin alpha-4, QIP1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
The nuclear import of karyophilic proteins is directed by short aa sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
Catalog #K0102-09J
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.2-1ug/ml
Immunohistochemistry (Paraffin embedded): Human Testis - shows strong nuclear staining of some cells in the seminiferous tubules. Recommended concentration, 3ug/ml. Human Small Intestine - shows pixulate staining in nuclei of enterocytes, 1-2ug/ml.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-NSSANVPTEGFQF, from KPNA4, at C-terminal (NP_002259.1).
SpecificityRecognizes human KPNA4. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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