Anti -Karyopherin beta 1 (KPNB1, Importin beta 1, IMB1, IPOB, Impnb, Importin 90, MGC2155,
MGC2156, MGC2157, Nuclear Factor p97, NTF97)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
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| Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. | | | Catalog # | K0102-30B | | Positive Control | Daudi cell lysate | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris-saline, pH7.2, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide, C-RRSKTNKAKTLAT, representing the C Terminus of the human protein according to NP_002256.2. Homology: Mouse, Rat, Dog | | Specificity | Species Crossreactivity: Human. Other species not tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Karyopherin beta 1 (KPNB1, Importin beta 1, IMB1, IPOB, Impnb, Importin 90, MGC2155, MGC2156, MGC2157, Nuclear Factor p97, NTF97) |
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