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Kazusamycin A (Kazusamycin, Hydroxyleptomycin B, Hydroxyelactocin, Antibiotic CL 1957B, Antibiotic PD 114721)
Kazusamycin A (Kazusamycin, Hydroxyleptomycin B, Hydroxyelactocin, Antibiotic CL 1957B,
Antibiotic PD 114721)
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| Kazusamycin A is a minor member of the leptomycin complex isolated from some Streptomyces species. It is an hydroxylated analogue of Leptomycin B, a nuclear export inhibitor. Kazusamycin A exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines and also shows strong antibacterial and antifungal activity. | | | Catalog # | K0108-85 | | Purity | >95% by HPLC | | Solubility | Soluble in ethanol or methanol. Ethanol recommended. Unstable in DMSO. | | Related to | Anguinomycin A, Leptomycin A, Leptomycin B, Kazusamycin B, | | CAS Number | 92090-94-3 | | Molecular Formula | C33H48O7 | | Molecular Weight | 556.7 | | Source | Streptomyces sp. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Kazusamycin, Hydroxyleptomycin B, Hydroxyelactocin, Antibiotic CL 1957B, Antibiotic PD 114721 |
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