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You are here:Home » Biochemicals » Biochem-Antibiotics » Kazusamycin B (Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895 )

Kazusamycin B (Hydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD
124,895 )

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Specifications

Kazusamycin B is a minor component of the leptomycin complex produced by some Streptomyces sp. It is an hydroxylated analogue of Leptomycin A, a nuclear export inhibitor. Kazusamycin B displays potent antitumour activity against L1210 and human colon adenocarcinoma and in vivo activity against P388 lymphocytic leukemia in mice. Kazusamycin B also possesses strong antibacterial and antifungal activity.
Catalog #K0108-85A
Purity >95% by HPLC
Solubility Soluble in ethanol or methanol. Ethanol recommended. Unstable in DMSO.
Related to Anguinomycin A, Leptomycin A, Leptomycin B, Kazusamycin A
CAS Number107140-30-7
Molecular FormulaC32H46O7
Molecular Weight542.7
SourceStreptomyces sp.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHydroxyleptomycin A, Antibiotic CL 1957E, Antibiotic PD 124895, 3. PD 124,895


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