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Specifications

Clone Host Grade Applications Polyclonal Guinea pig Serum IF

A wide variety of cells contain, in addition to microtubules and microfilaments, another type of fibrous skeletal element which are classified under the category of "intermediate-sized" filaments. These intermediate sized filaments are stable in vivo and show a biochemical heterogeneity which is developmentally regulated.Each class of intermediate filament is restricted in vivo by tissue differentiation; keratins to epithelia, vimentin to mesenchymal cells, desmin to muscle tissues, glial fibrillary acidic protein (GFAP) to astroglia and neurofilament proteins to neurones. Unlike actin and tubulin, where molecular size is highly conserved from cell to cell and species to species, intermediate filament proteins vary greatly in size from class to class as well as species to species.
Catalog #	K0199-03
Applications	Suitable for use in Immunofluorescence. Other applications not tested.
Recommended Dilution	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Guinea pig
Source	Bovine
Concentration	As reported
Form	0.1% Sodium Azide; Whole Serum
Purity	Whole antisera
Immunogen	Keratin isolated from fetal bovine hooves.
Specificity	Does not react with mesenchymal, glial, neuronal or muscle cells. Species Crossreactivity: Crossreacts with Human and bovine. Not yet tested in other species.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.